Relationship between Central Corneal Thickness, Vitreous Chamber Depth and Axial Length of Adults in a Nigerian Population.

Iyamu E1 and Okukpon J.O1

  1. Department of Optometry, Faculty of Life Sciences, University of Benin, Benin City, Edo State.

Corresponding Author: Juno Ohiremere Okukpon, Email: Phone: 08036899420


The central corneal thickness (CCT), Vitreous chamber depth (VCD) and axial length (AL) are important ocular parameters used in the assessment of ocular health in relation to some ocular morbidities. Determining the differences in these parameters in relation to each other is fundamental to understanding the general eye health and also aid in developing strategies to help early diagnoses and management of some ocular conditions. Sixty-six (66) participants consisting of thirty-one (31) males and thirty-five (35) females between 18 to 68 years participated in this study. CCT and other ocular biometry were measured with Ultrasound pachymetry and ultrasonography. VCD was obtained by subtracting the sum of anterior chamber depth and lens thickness, from AL. All data were analyzed with Statgraphics plus version 5.1 and SPSS version 22.0. The mean age, CCT, VCD and AL were 37.2 ± 11.6 years, 536.71±23.89 μm, 16.30±0.80mm and 23.60±0.80mm respectively. Statistically significant positive correlation was found between VCD and AL (r= 0.83, r2= 69.3%, p<0.0001). The difference in mean VCD (0.49mm) between males (16.63±0.89mm) and females (16.14±0.66mm) was statistically significant (p= 0.015). Similarly, the difference in mean AL (0.54mm) between males (23.89±0.78mm) and females (23.35 ± 0.74mm) was statistically significant (p= 0.005). The linear association between CCT, VCD and AL was not significant. AL and VCD were not significantly affected by age but a significant negative linear relationship was found between CCT and age. The result of this study will aid in early diagnoses of some ocular morbidity by identifying risk factors associated with these parameters.

Keywords: Central corneal thickness, Vitreous chamber depth, Axial length

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